Watson and Crick: The Discovery of the DNA Structure.
Watson and Crick model of DNA provides one of the best ways to demonstrate the structure of double helix DNA.A DNA is a polymer which is composed by the combination of several monomer units refers as “Deoxyribo nucleotides” linked by the phosphodiester bond.In the discovery of DNA, many scientists have explicated the structure of DNA, its components and composition etc.
Maurice Wilkins is not credited for the actual discovery of the structure of DNA rather that distinction goes to James Watson and Francis Crick and is known as the Watson-Crick model. Wilkins did share in the Nobel prize because his work in spectroscopic studies on nucleic acids led to the use of X-ray crystallography to define the Watson-Crick model of DNA.
Watson and Crick were attempting to discover the structure of DNA in the early 1950s at Cambridge University, racing against Maurice Wilkins and Rosalind Franklin at King’s College. Wilkins and Franklin used an experimental approach to the study, according to nobelprize.org, “using x-ray diffraction to understand the physical structure of the DNA molecule.”.
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Spring 1953 Watson and Crick was given official orders to work structure of DNA again They needed more information, they needed to figure out how the four components of DNA went together.Erwin Chargaff was the key. Watson and Crick were bubbling at the fact that they had another chance to find out the structure of DNA.
Maurice Wilkins and Medical Research Council Biophysics Unit archive Maurice Wilkins began the studies on the crystalline structure of DNA that ultimately led to the discovery of the double helix by James Watson and Francis Crick. Open the Wilkins archive View digitised items online.
Watson and Crick took a crucial conceptual step, suggesting the molecule was made of two chains of nucleotides, each in a helix as Franklin had found, but one going up and the other going down.